LPAR1 polyclonal antibody
产品名称： LPAR1 polyclonal antibody
英文名称： LPAR1 polyclonal antibody
产品编号： PAB10126
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LPAR1.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of LPAR1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western blot (5 to 10 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Lysophosphatidic acid receptor-selective effects on Jurkat T cell migration through a Matrigel model basement membrane.
Zheng Y, Kong Y, Goetzl EJ.J Immunol. 2001 Feb 15;166(4):2317-22.
- 2.
- Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax.
Goetzl EJ, Kong Y, Mei B.J Immunol. 1999 Feb 15;162(4):2049-56.
- 3.
- A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid.
Fukushima N, Kimura Y, Chun J.Proc Natl Acad Sci U S A. 1998 May 26;95(11):6151-6.
- Entrez GeneID:
- 1902
- Gene Name:
- LPAR1
- Gene Alias:
- EDG2,GPR26,Gpcr26,LPA1,Mrec1.3,VZG1,edg-2,rec.1.3,vzg-1
- Gene Description:
- lysophosphatidic acid receptor 1
- Omim ID:
- 602282
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq
- Other Designations:
- OTTHUMP00000021903,OTTHUMP00000021904,OTTHUMP00000021905,endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2,ventricular zone gene 1
- Gene Pathway