产品概述：Purified recombinant protein of Human natriuretic peptide B (NPPB), N-terminal His and ABP tag, expressed in E. coli, 50ug

蛋白长度：A DNA sequence encoding the region(His27-Arg102) of NPPB

表达系统：E. coli

种属：Human

标签类型：N-His-ABP

分子量：23.8 kDa

通用名：NPPB

总结：This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Aug 2020]

形式：Liquid

浓度：>50 ug/mL as determined by Bradford protein assay method.

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：PBS, pH7.4, 10% glycerol

别名：BNP; Iso-ANP